The University of the Philippines Association of Chemistry Majors and Enthusiasts (UP ACME) is a non-political, non-stock, non-profit, student-oriented academic organization based in the Institute of Chemistry, College of Science.

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Established in 1997, UP ACME is aimed at promoting academic excellence while developing leaders with high sense of responsibility, which is exemplified by promoting camaraderie and well-rounded development among its members, and undertaking activities for the promotion and appreciation of Chemistry.

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Dissolved in 2006 but was reestablished two years later, UP ACME continues to safeguard its honor, maintain its integrity and promote a sense of loyalty among its members, led by the member-elected Executive Committee which, through collective efforts, help in enhancing the physical, intellectual and social well-being of its members.

UP ACME fulfills a legacy of excellence by the roster of its motivated members, mentored by senior adviser Guillermo Nuesca, Ph.D. and junior adviser Lawrence John Paulo Trinidad, geared at uplifting Chemistry in the Philippine setting.